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1

Cornerstones of CRISPR–Cas in drug discovery and therapy

Fellmann, Christof, Gowen, Benjamin G., Lin, Pei-Chun, Doudna, Jennifer A., Corn, Jacob E.

Journal:

Nature Reviews Drug Discovery

Année:

2016

Langue:

english

Fichier:

PDF, 3.97 MB

english, 2016

2

CRISPR germline engineering—the community speaks

Bosley, Katrine S, Botchan, Michael, Bredenoord, Annelien L, Carroll, Dana, Charo, R Alta, Charpentier, Emmanuelle, Cohen, Ron, Corn, Jacob, Doudna, Jennifer, Feng, Guoping, Greely, Henry T, Isasi, Ro

Journal:

Nature Biotechnology

Année:

2015

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2015

3

Synthesis of high active catalytic systems based on double molybdenum carbides

Dolmatov Vladimir,Kuznetsov Sergey,Rebrov Evgeny,Schouten Jacob Cornelis

Journal:

Труды Кольского научного центра РАН

Année:

2015

Langue:

english

Fichier:

PDF, 6.16 MB

english, 2015

4

Production of Human Recombinant Proapolipoprotein A-I in Escherichia coli : Purification and Biochemical Characterization

MOGUILEVSKY, NICOLE, ROOBOL, CORNELIS, LORIAU, ROSETTE, GUILLAUME, JEAN-PAUL, JACOBS, PAUL, CRAVADOR, ALFREDO, HERZOG, ALBERT, BROUWERS, LÉON, SCARSO, ALAIN, GILLES, PASCAL, HOLMQUIST, LEIF, CARLSON,

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 3.31 MB

english, 1989

5

CRISPR off-target detection with DISCOVER-seq

Wienert, Beeke, Wyman, Stacia K., Yeh, Charles D., Conklin, Bruce R., Corn, Jacob E.

Journal:

Nature Protocols

Année:

2020

Fichier:

PDF, 1.48 MB

2020

6

Vaccine-specific local T cell reactivity in immunotherapy-associated vitiligo in melanoma patients

Joannes F. M. Jacobs, Erik H. J. G. Aarntzen, Lenny A. G. Sibelt, Willeke A. Blokx, Anna C. I. Boullart, Marie-Jeanne Gerritsen, Peter M. Hoogerbrugge, Carl G. Figdor, Gosse J. Adema, Cornelis J. A. P

Journal:

Cancer Immunology, Immunotherapy

Année:

2009

Langue:

english

Fichier:

PDF, 443 KB

english, 2009

7

Effects of aging on brain perfusion and serotonin-2A receptor binding in the normal canine brain measured with single photon emission tomography

Kathelijne Peremans, Kurt Audenaert, Peter Blanckaert, Filip Jacobs, Frank Coopman, Francis Verschooten, Henri Van Bree, Cornelis Van Heeringen, John Mertens, Guido Slegers, Rudi Dierckx

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Année:

2002

Langue:

english

Fichier:

PDF, 245 KB

english, 2002

8

Suppression effectiveness of water-mist sprays on accelerated wood-crib fires

Santangelo, Paolo E., Jacobs, Bryson C., Ren, Ning, Sheffel, Joshua A., Corn, May L., Marshall, André W.

Journal:

Fire Safety Journal

Année:

2014

Langue:

english

Fichier:

PDF, 7.97 MB

english, 2014

9

Outcome After Operative Fusion of the Tarsal Joints: A Systematic Review

Stegeman, Mark, Louwerens, Jan Willem Karel, van der Woude, Jan Ton, Jacobs, Wilhelmus Cornelis Hermina, van Ginneken, Berbke To Josephine

Journal:

The Journal of Foot and Ankle Surgery

Année:

2015

Langue:

english

Fichier:

PDF, 323 KB

english, 2015

10

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

Richardson, Christopher D, Ray, Graham J, DeWitt, Mark A, Curie, Gemma L, Corn, Jacob E

Journal:

Nature Biotechnology

Année:

2016

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2016

11

Disabling Cas9 by an anti-CRISPR DNA mimic

Shin, Jiyung, Jiang, Fuguo, Liu, Jun-Jie, Bray, Nicolas L., Rauch, Benjamin J., Baik, Seung Hyun, Nogales, Eva, Bondy-Denomy, Joseph, Corn, Jacob E., Doudna, Jennifer A.

Journal:

Science Advances

Année:

2017

Langue:

english

Fichier:

PDF, 5.79 MB

english, 2017

12

BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes

Stewart, Mikaela D., Zelin, Elena, Dhall, Abhinav, Walsh, Tom, Upadhyay, Esha, Corn, Jacob E., Chatterjee, Champak, King, Mary-Claire, Klevit, Rachel E.

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 920 KB

english, 2018

13

Caramel colour and process contaminants in foods and beverages: Part II - Occurrence data and exposure assessment of 2-acetyl-4-(1,2,3,4-tetrahydroxybutyl)imidazole (THI) and 4-methylimidazole (4-MEI) in Belgium

Fierens, T., Van Holderbeke, M., Cornelis, C., Jacobs, G., Sioen, I., De Maeyer, M., Vinkx, C., Vanermen, G.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 511 KB

english, 2018

14

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Farboud, Behnom, Jarvis, Erin, Roth, Theodore L., Shin, Jiyung, Corn, Jacob E., Marson, Alexander, Meyer, Barbara J., Patel, Nipam H., Hochstrasser, Megan L.

Journal:

Journal of Visualized Experiments

Année:

2018

Langue:

english

Fichier:

PDF, 639 KB

english, 2018

15

Synthetically modified guide RNA and donor DNA are a versatile platform for CRISPR-Cas9 engineering

Lee, Kunwoo, Mackley, Vanessa A, Rao, Anirudh, Chong, Anthony T, Dewitt, Mark A, Corn, Jacob E, Murthy, Niren

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.23 MB

english, 2017

16

Sometimes you’re the scooper, and sometimes you get scooped: How to turn both into something good

Kim, Jin-Soo, Corn, Jacob E.

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 451 KB

english, 2018

17

CRISPR-Cas9 interrogation of a putative fetal globin repressor in human erythroid cells

Chung, Jennifer E., Magis, Wendy, Vu, Jonathan, Heo, Seok-Jin, Wartiovaara, Kirmo, Walters, Mark C., Kurita, Ryo, Nakamura, Yukio, Boffelli, Dario, Martin, David I. K., Corn, Jacob E., DeWitt, Mark A.

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 708 KB

english, 2019

18

A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

Liang, Jin Rui, Lingeman, Emily, Luong, Thao, Ahmed, Saba, Muhar, Matthias, Nguyen, Truc, Olzmann, James A., Corn, Jacob E.

Journal:

Année:

2020

Fichier:

PDF, 8.69 MB

2020

19

Photoinduced Intramolecular Charge Separation in Donor/Acceptor-Substituted Bicyclohexylidene and Bicyclohexyl

Frans J. Hoogesteger, Cornelis A. van Walree, Leonardus W. Jenneskens, Martin R. Roest, Jan W. Verhoeven, Wouter Schuddeboom, Jacob J. Piet, John M. Warman

Journal:

Chemistry - A European Journal

Année:

2000

Langue:

english

Fichier:

PDF, 324 KB

english, 2000

20

Common variants in the TPH1 and TPH2 regions are not associated with persistent ADHD in a combined sample of 1,636 adult cases and 1,923 controls from four European populations

Stefan Johansson, Anne Halmøy, Thegna Mavroconstanti, Kaya K. Jacobsen, Elisabeth T. Landaas, Andreas Reif, Christian Jacob, Andrea Boreatti-Hümmer, Susanne Kreiker, Klaus-Peter Lesch, Cornelis C. Kan

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Année:

2010

Langue:

english

Fichier:

PDF, 263 KB

english, 2010

21

Mutations in the major histocompatibility complex class I antigen-presenting groove affect both negative and positive selection of T cells

Heinz Jacobs, Harald Von Boehmer, Cornelis J. M. Melief, Anton Berns

Journal:

European Journal of Immunology

Année:

1990

Langue:

english

Fichier:

PDF, 474 KB

english, 1990

22

Photoinduced Charge Separation in Cyclohexylidene-Based Donor−(σ-Bridge)−Acceptor Compounds − Building Blocks for Materials

Wibren D. Oosterbaan, Paul C. M. van Gerven, Cornelis A. van Walree, Mattijs Koeberg, Jacob J. Piet, Remco W. A. Havenith, Jan W. Zwikker, Leonardus W. Jenneskens, Rolf Gleiter

Journal:

European Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 243 KB

english, 2003

23

Frequency and degree of aneuploidy in benign and malignant thyroid neoplasms

Lodewijk J. D. M. Schelfhout, Cees J. Cornelisse, Bernard M. Goslings, Jacob F. Hamming, Nel J. Kuipers-Dijkshoorn, Cornelis J. H. van de Velde, Gert Jan Fleuren

Journal:

International Journal of Cancer

Année:

1990

Langue:

english

Fichier:

PDF, 537 KB

english, 1990

24

Electron beam therapy is not inferior to superficial x-ray therapy in the treatment of skin carcinoma

Cornelis Griep, Jacob Davelaar, Astrid N. Scholten, Alim Chin, Jan-Willem H. Leer

Journal:

International Journal of Radiation Oncology*Biology*Physics

Année:

1995

Langue:

english

Fichier:

PDF, 716 KB

english, 1995

25

Microfocus X-ray computed tomography analysis of corroded glass objects

Florias Mees, Etienne Cornelis, Patric Jacobs, Maria Teresa Doménech Cárbo, Hannelore Römich

Journal:

Engineering Geology

Année:

2009

Langue:

english

Fichier:

PDF, 1.75 MB

english, 2009

26

Determination of succinylacetone in dried blood spots and liquid urine as a dansylhydrazone by liquid chromatography tandem mass spectrometry

Osama Y. Al-Dirbashi, Mohamed S. Rashed, Herman J. Ten Brink, Cornelis Jakobs, Najlaa Filimban, Lujane Y. Al-Ahaidib, Minnie Jacob, Moeen M. Al-Sayed, Zuhair Al-Hassnan, Eissa Faqeih

Journal:

Journal of Chromatography B

Année:

2006

Langue:

english

Fichier:

PDF, 157 KB

english, 2006

27

Discrimination between the anti-monomeric and the anti-multimeric Lewis X response in murine schistosomiasis

Anne-Marie M. Van Roon, Koen K. Van de Vijver, Werner Jacobs, Eric A. Van Marck, Govert J. Van Dam, Cornelis H. Hokke, André M. Deelder

Journal:

Microbes and Infection

Année:

2004

Langue:

english

Fichier:

PDF, 363 KB

english, 2004

28

Automated electron-density sampling reveals widespread conformational polymorphism in proteins

P. Therese Lang, Ho-Leung Ng, James S. Fraser, Jacob E. Corn, Nathaniel Echols, Mark Sales, James M. Holton, Tom Alber

Journal:

Protein Science

Année:

2010

Langue:

english

Fichier:

PDF, 631 KB

english, 2010

29

Rosetta in CAPRI rounds 13–19

Sarel J. Fleishman, Jacob E. Corn, Eva M. Strauch, Tim A. Whitehead, Ingemar Andre, James Thompson, James J. Havranek, Rhiju Das, Philip Bradley, David Baker

Journal:

Proteins: Structure, Function, and Bioinformatics

Année:

2010

Langue:

english

Fichier:

PDF, 286 KB

english, 2010

30

Simultaneous expression of the S and L surface antigens of hepatitis B, and formation of mixed particles in the methylotrophic yeast, Hansenula polymorpha

Zbigniew A. Janowicz, Karl Melber, Armin Merckelbach, Eric Jacobs, Nigel Harford, Martin Comberbach, Cornelis P. Hollenberg

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1991

31

Technetium-99m dimercaptosuccinic acid and ifosfamide tubular dysfunction in children with cancer

Jacob K. Anninga, Renato A. Valdés Olmos, Jan Kraker, Harm Tinteren, Cornelis A. Hoefnagel, Eric A. Royen

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Année:

1994

Langue:

english

Fichier:

PDF, 746 KB

english, 1994

32

Herpes simplex virus load in bronchoalveolar lavage fluid is related to poor outcome in critically ill patients

Catharina F. M. Linssen, Jan A. Jacobs, Foekje F. Stelma, Walther N. K. A. van Mook, Peter Terporten, Cornelis Vink, Marjolein Drent, Cathrien A. Bruggeman, Annick Smismans

Journal:

Intensive Care Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 271 KB

english, 2008

33

Small Bowel Volvulus Diagnosed by the CT “Whirl Sign”

Niels de Korte, Cornelis T. Grutters, Jacob P. Snellen

Journal:

Journal of Gastrointestinal Surgery

Année:

2008

Langue:

english

Fichier:

PDF, 96 KB

english, 2008

34

Bioactive TGF-β can associate with lipoproteins and is enriched in those containing apolipoprotein E3

Ina Tesseur, Hui Zhang, Walter Brecht, Jacob Corn, Jian-Sheng Gong, Katsuhiko Yanagisawa, Makoto Michikawa, Karl Weisgraber, Yadong Huang, Tony Wyss-Coray

Journal:

Journal of Neurochemistry

Année:

2009

Langue:

english

Fichier:

PDF, 791 KB

english, 2009

35

Sklyarov: big business vs academic freedom

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 37 KB

english, 2002

36

Identification of a DNA primase template tracking site redefines the geometry of primer synthesis

Corn, Jacob E, Pelton, Jeffrey G, Berger, James M

Journal:

Nature Structural and Molecular Biology

Année:

2008

Langue:

english

Fichier:

PDF, 819 KB

english, 2008

37

THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves

Sabogal, Alex, Lyubimov, Artem Y, Corn, Jacob E, Berger, James M, Rio, Donald C

Journal:

Nature Structural and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2009

38

Estimating the impact of regional policy: A review of applied research methods

Cornelis P.A. Bartels, William R. Nicol, Jacob J. van Duijn

Journal:

Regional Science and Urban Economics

Année:

1982

Langue:

english

Fichier:

PDF, 4.38 MB

english, 1982

39

Prognostic Value of Renal Dysfunction for the Prediction of Outcome Versus Results of Computed Tomographic Coronary Angiography

Kai Hang Yiu, Fleur R. de Graaf, Joanne D. Schuijf, Jacob M. van Werkhoven, Joella E. van Velzen, Mark J. Boogers, Cornelis J. Roos, Mihály K. de Bie, Aju Pazhenkottil, Lucia J. Kroft, Eric Boersma, B

Journal:

The American Journal of Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 269 KB

english, 2011

40

Glycans of Schistosoma mansoni and keyhole limpet haemocyanin induce hepatic granulomas in vivo

Koen K Van de Vijver, Cornelis H Hokke, Alexandra van Remoortere, Werner Jacobs, André M Deelder, Eric A Van Marck

Journal:

International Journal for Parasitology

Année:

2004

Langue:

english

Fichier:

PDF, 586 KB

english, 2004

41

The optical evaluation of atmospheric dustfall

Morton Corn, Robert Quinlan, Jacob Katz

Journal:

Atmospheric Environment (1967)

Année:

1967

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1967

42

The host's genetic background determines the extent of angiogenesis induced by schistosome egg antigens

Koen K. Van de Vijver, Cecile G. Colpaert, Werner Jacobs, Kristel Kuypers, Cornelis H. Hokke, André M. Deelder, Eric A. Van Marck

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 891 KB

english, 2006

43

Magnetic microstructures of metal grains in equilibrated ordinary chondrites and implications for paleomagnetism of meteorites

Minoru Uehara, Jérôme Gattacceca, Hugues Leroux, Damien Jacob, Cornelis Jacominus van der Beek

Journal:

Earth and Planetary Science Letters

Année:

2011

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2011

44

High-fat enteral nutrition reduces endotoxin, tumor necrosis factor-alpha and gut permeability in bile duct-ligated rats subjected to hemorrhagic shock

Misha D.P. Luyer, Wim A. Buurman, M'hamed Hadfoune, Jan A. Jacobs, Cornelis H.C. Dejong, Jan Willem M. Greve

Journal:

Journal of Hepatology

Année:

2004

Langue:

english

Fichier:

PDF, 262 KB

english, 2004

45

Community-Wide Assessment of Protein-Interface Modeling Suggests Improvements to Design Methodology

Sarel J. Fleishman, Timothy A. Whitehead, Eva-Maria Strauch, Jacob E. Corn, Sanbo Qin, Huan-Xiang Zhou, Julie C. Mitchell, Omar N.A. Demerdash, Mayuko Takeda-Shitaka, Genki Terashi, Iain H. Moal, Xiao

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 548 KB

english, 2011

46

Hotspot-Centric De Novo Design of Protein Binders

Sarel J. Fleishman, Jacob E. Corn, Eva-Maria Strauch, Timothy A. Whitehead, John Karanicolas, David Baker

Journal:

Journal of Molecular Biology

Année:

2011

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2011

47

Rapid identification of bacteria by real-time amplification and sequencing of the 16S rRNA gene

Inge Vliegen, Jan A. Jacobs, Erik Beuken, Cathrien A. Bruggeman, Cornelis Vink

Journal:

Journal of Microbiological Methods

Année:

2006

Langue:

english

Fichier:

PDF, 768 KB

english, 2006

48

Rapid and reliable identification of Streptococcus anginosus group isolates to the species level by real-time PCR and melting curve analysis

Ingrid M.E. Desar, Maaike de Boer, Corina C.P.M. Bens, Jan A. Jacobs, Johan W. Mouton, Anton S.M. Dofferhoff, Corné H.W. Klaassen

Journal:

Journal of Microbiological Methods

Année:

2008

Langue:

english

Fichier:

PDF, 189 KB

english, 2008

49

Crosstalk between Primase Subunits Can Act to Regulate Primer Synthesis in trans

Jacob E. Corn, Paul J. Pease, Greg L. Hura, James M. Berger

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 603 KB

english, 2005

50

A De Novo Protein Binding Pair By Computational Design and Directed Evolution

John Karanicolas, Jacob E. Corn, Irwin Chen, Lukasz A. Joachimiak, Orly Dym, Sun H. Peck, Shira Albeck, Tamar Unger, Wenxin Hu, Gaohua Liu, Scott Delbecq, Gaetano T. Montelione, Clint P. Spiegel, Davi

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2011